The John McNicholas Pediatric Brain Tumor Foundation differs from many other foundations in two important respects. First, 100% of the money you commit goes into furthering our mission. Second, our mission is forward focused. We will change the landscape of pediatric brain tumor research by funding novel proposals targeted at moving forward in the care and treatment of pediatric brain tumor patients. Better care; better cure. It’s an ambitious goal, and that‘s why we need your help.

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Modifying the Future

Modifying the Future is our most ambitious and exciting program to-date, aimed at pioneering cutting-edge research for pediatric brain tumors. Today, children diagnosed with brain cancer are treated with the same drugs and therapies that existed over 30 years ago. There have been no new advancements made in decades, and such low funding that there’s no hope for change.

But here at the John McNicholas Pediatric Brain Tumor Foundation, we’re setting out to change that.

Today, Modifying the Future is poised on the brink of something big: With generous support from friends like you, we’re able to get much-needed funds directly into the hands of the most promising and innovative doctors and research scientists. With the funding they need, this team can deliver real and rapid results that save children’s lives.

The Dream Team

Together, in partnership with Ann & Robert H. Lurie Children’s Hospital and Northwestern University Feinberg School of Medicine, we’ve created a research Dream Team of the best and brightest to dedicate their skill to finding a cure.

Pictured from left to right:
Our Dream Team is committed to studying high-grade gliomas—the deadliest and most common form of brain tumors. 
With a multidisciplinary approach, these doctors cover the entire range of the research process—from extracting tissue samples and developing new therapies, to exploring novel delivery techniques that are safer and more effective for our kids. Our Dream Team is leading the charge on new therapies and treatment options—and will bring their best findings to our children’s bedsides through life-changing clinical trials.

While there are many talented groups pursuing important work in this area, the collaborative spirit and collective potential of our Dream Team is second to none. Their expertise centers around one of the most promising discoveries in pediatric brain tumor biology made in nearly 40 years—the high prevalence of Histone 3 mutation. This team’s experience and passion is truly one of a kind, and their work has the potential to translate into real hope for our children.

How you can help?

Modifying the Future is the most exciting and promising step we’ve taken thus far—but we need your support to make a difference. Please consider making a generous, tax-deductible gift to the John McNicholas Pediatric Brain Tumor Foundation. When you join our fight today, you empower our Dream Team to make the impossible possible.


We have put together a multidisciplinary medical advisory board which will represent some of the best and brightest clinicians from around the country to help guide us in identifying and funding specifically targeted pediatric brain tumor research and treatment options to achieve our ultimate goal: the eradication of pediatric brain tumors.


The John McNicholas Pediatric Brain Tumor Foundation is a 501(c)3 non-profit organization that is funded through donations from friends like you! Please donate today and help us further our mission to eradicate pediatric brain tumors.


Consider naming our Foundation or Partners for tributes when remembering loved ones or to honor someone special. Obviously, we understand the desire to mark the passing of those special to us. We will direct these memorial donations to fund specifically targeted pediatric brain tumor research and treatment options that will impact the lives of those afflicted now and forever!


Over 15,000 US corporations match gifts … does yours?
Many employers sponsor matching gift programs and will match charitable contributions made by their employees. Please check with your HR Department to find out if your gift can be matched. Corporate matching can double or even triple your gift. Please donate today!


The Foundation and Partners host several events each year, and we are always looking to expand! Let us know if you are interested in bringing our “Go Gray in May” program to your school or office. Or start something new, we are looking for new, creative ways to communicate our mission, educating the masses, and increase our power to raise money to support our cause. Click here to visit our Fundraisers section in our Get Involved page.
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e: [email protected]
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